Issue 10, 2017
From the journal:

Inorganic Chemistry Frontiers

201Tl-labeled Prussian blue and Au@Prussian blue nanoprobes for SPEC-CT imaging: influence of the size, shape and coating on the biodistribution†

Guillaume Maurin-Pasturel,a   Estelle Rascol,b   Muriel Busson,c   Samuel Sevestre,c   Joséphine Lai-Kee-Him,d   Patrick Bron,d   Jérôme Long, ORCID logo a   Joël Chopineau,*be   Jean-Marie Devoisselle,b   Yannick Guari ORCID logo a  and  Joulia Larionova ORCID logo *c  

* Corresponding authors

a Institut Charles Gerhardt Montpellier, UMR 5253, Ingénierie Moléculaire et Nano-Objets, Univ. Montpellier, CNRS, ENSCM, Place E. Bataillon, 34095 Montpellier Cedex 5, France

b Institut Charles Gerhardt Montpellier, UMR 5253, Matériaux Avancés pour la Catalyse et la Santé, Univ. Montpellier, ENSCM, CNRS, 15, avenue Charles Flahault, 34093 Montpellier Cedex 5, France
E-mail: joel.chopineau@enscm.fr

c Institut de Recherche en Cancérologie de Montpellier, INSERM, U896, Univ. Montpellier, 124, Avenue des Apothicaires, 34090 Montpellier, France
E-mail: joulia.larionova@umontpellier.fr

d Centre de biochimie structurale CNRS UMR 5048, INSERM U 1054, Univ. Montpellier, 29, rue de Navacelles, 34090 Montpellier, France

e Université de Nîmes Rue Georges Salan, 30000 Nîmes, France

Abstract

201Tl-labeled Prussian blue and Au core@Prussian blue shell nanoparticles were synthesised and investigated in vivo as nanoprobes by using SPECT-CT scintigraphy. We demonstrate that the size, morphology and nanoparticle coating affect the kinetics of the nanoparticle biodistribution.

Graphical abstract: 201Tl-labeled Prussian blue and Au@Prussian blue nanoprobes for SPEC-CT imaging: influence of the size, shape and coating on the biodistribution

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Article information

DOI
https://doi.org/10.1039/C7QI00321H
Article type
Research Article
Submitted
08 Jun 2017
Accepted
04 Aug 2017
First published
23 Aug 2017

Inorg. Chem. Front., 2017,4, 1737-1741

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201Tl-labeled Prussian blue and Au@Prussian blue nanoprobes for SPEC-CT imaging: influence of the size, shape and coating on the biodistribution

G. Maurin-Pasturel, E. Rascol, M. Busson, S. Sevestre, J. Lai-Kee-Him, P. Bron, J. Long, J. Chopineau, J. Devoisselle, Y. Guari and J. Larionova, Inorg. Chem. Front., 2017, 4, 1737 DOI: 10.1039/C7QI00321H

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