Efficient synthesis of multisubstituted 2-alkenylpyridines via 2,3-rearrangement of O-homoallenylic oximes

Abstract

O-Homoallenylic α,β-unsaturated oximes were efficiently converted to the corresponding 2-alkenylpyridine derivatives by microwave irradiation. The present reaction proceeds via 2,3-rearrangement followed by 6π-electrocyclization of the resulting N-(2-dienyl)nitrone intermediate serving as a 3-azatriene.