Issue 17, 2017, Issue in Progress

Fabrication of a silver octahedral nanoparticle-containing polycaprolactone nanocomposite for antibacterial bone scaffolds

Abstract

This work investigated the antimicrobial activity of Ag octahedral nanoparticle containing polycaprolactone scaffolds (Ag–PCL) that is fabricated via cryomilling. The fabricated composite scaffolds exhibited localized antibacterial activity with no adverse effects on viability and osteogenic differentiation of human fetal mesenchymal stem cells (hfMSCs). Compared to plain PCL scaffolds, the Ag–PCL scaffolds significantly reduce bacteria survival to 32.2% over a 4 hour incubation.

Graphical abstract: Fabrication of a silver octahedral nanoparticle-containing polycaprolactone nanocomposite for antibacterial bone scaffolds

Supplementary files

Article information

Article type
Paper
Submitted
31 Oct 2016
Accepted
30 Jan 2017
First published
06 Feb 2017
This article is Open Access
Creative Commons BY-NC license

RSC Adv., 2017,7, 10051-10056

Fabrication of a silver octahedral nanoparticle-containing polycaprolactone nanocomposite for antibacterial bone scaffolds

Y. Gao, A. M. Hassanbhai, J. Lim, L. Wang and C. Xu, RSC Adv., 2017, 7, 10051 DOI: 10.1039/C6RA26063B

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