One-pot synthesis of a DNA-anchored SERS nanoprobe with simultaneous nanostructural tuning and Raman reporter encoding

Yun Li; Xiangjiang Liu; Di Jiang; Zhongzhi Yu; Dalin Tian; Chang Lu; Mingyu Li; Jianjun He; Longhua Tang

doi:10.1039/C6RA26580D

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One-pot synthesis of a DNA-anchored SERS nanoprobe with simultaneous nanostructural tuning and Raman reporter encoding†

Yun Li,‡^a Xiangjiang Liu,

‡^b Di Jiang,^a Zhongzhi Yu,^a Dalin Tian,^a Chang Lu,^b Mingyu Li,^a Jianjun He^a and Longhua Tang

*^a

Author affiliations

* Corresponding authors

^a State Key Laboratory of Modern Optical Instrumentation, College of Opticall Science and Engineering, Zhejiang University, Hangzhou 310027, China
E-mail: lhtang@zju.edu.cn

^b College of Biosystems Engineering and Food Science, Zhejiang University, Hangzhou 310058, China

Abstract

We report a new simple synthesis method for a DNA-anchored SERS nanoprobe encoded with a Raman reporter by a one-pot overgrowth process, allowing the nanostructure to be controllably tuned to provide improved Raman enhancement, and simultaneously introduce Raman reporters and DNA onto nanoparticles whilst retaining their SERS activity and bio-recognition ability.

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Article information

DOI: https://doi.org/10.1039/C6RA26580D
Article type: Paper
Submitted: 09 Nov 2016
Accepted: 31 Dec 2016
First published: 17 Jan 2017
This article is Open Access

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RSC Adv., 2017,7, 5063-5066

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One-pot synthesis of a DNA-anchored SERS nanoprobe with simultaneous nanostructural tuning and Raman reporter encoding

Y. Li, X. Liu, D. Jiang, Z. Yu, D. Tian, C. Lu, M. Li, J. He and L. Tang, RSC Adv., 2017, 7, 5063 DOI: 10.1039/C6RA26580D

This article is licensed under a Creative Commons Attribution 3.0 Unported Licence. You can use material from this article in other publications without requesting further permissions from the RSC, provided that the correct acknowledgement is given.

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One-pot synthesis of a DNA-anchored SERS nanoprobe with simultaneous nanostructural tuning and Raman reporter encoding†

Abstract

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One-pot synthesis of a DNA-anchored SERS nanoprobe with simultaneous nanostructural tuning and Raman reporter encoding

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