Highly stable and biocompatible W18O49@PEG-PCL hybrid nanospheres combining CT imaging and cancer photothermal therapy

Abstract

In this study, we encapsulated W₁₈O₄₉ NPs with PEG-PCL NPs (W₁₈O₄₉@PEG-PCL NPs). The PEG-PCL NPs enhance the biocompatibility, stability and internalization of the W₁₈O₄₉ NPs in cells. Retained for a long time, these W₁₈O₄₉@PEG-PCL NPs possess excellent CT efficiency and superior PTT potency, which confer them with the potential to play an active role in future clinical trials.