Issue 46, 2017, Issue in Progress

A multianalyte fluorescent carbon dots sensing system constructed based on specific recognition of Fe(iii) ions

Abstract

In this research, we developed a multianalyte fluorescence sensing system through a carbon dots (CDs)-based fluorescent probe that can specifically recognize Fe(III) by fluorescence quenching. The CDs prepared using black tea by a hydrothermal method show outstanding properties like low cytotoxicity, high photostability, excellent biocompatibility, and high sensitivity. It was found that the fluorescence of CDs can be quenched by micromolar concentrations of Fe(III) in both aqueous solutions as well as living cells. It is well known that glucose can be oxidized by glucose oxidase (GOx) to release H2O2, which, in turn, can oxidize Fe(II) to Fe(III). Based on this consideration, a multianalyte sensing system was established. Therefore the quantitative analysis of Fe(III), H2O2, and glucose with detection limits of 0.25 μM, 0.82 μM, and 1.71 μM, respectively, was achieved by the simple and cost-effective multianalyte CDs sensing system constructed. The sensing system showed high photostability and negligible cytotoxicity toward HeLa cells, which enables it to be applied in the visualization of Fe(III) or H2O2 in living cells. The system was further applied in the detection of Fe(III) or glucose in human serum, and satisfactory results were obtained.

Graphical abstract: A multianalyte fluorescent carbon dots sensing system constructed based on specific recognition of Fe(iii) ions

Supplementary files

Article information

Article type
Paper
Submitted
11 Apr 2017
Accepted
12 May 2017
First published
31 May 2017
This article is Open Access
Creative Commons BY license

RSC Adv., 2017,7, 28637-28646

A multianalyte fluorescent carbon dots sensing system constructed based on specific recognition of Fe(III) ions

P. Song, L. Zhang, H. Long, M. Meng, T. Liu, Y. Yin and R. Xi, RSC Adv., 2017, 7, 28637 DOI: 10.1039/C7RA04122E

This article is licensed under a Creative Commons Attribution 3.0 Unported Licence. You can use material from this article in other publications without requesting further permissions from the RSC, provided that the correct acknowledgement is given.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements