Issue 60, 2017, Issue in Progress
From the journal:

RSC Advances

Copper-catalyzed one-pot reactions of acetyl chloride, o-halobenzoic acids and Wittig reagents toward 3-methyl isocoumarin synthesis†

Xuwen Chena  and  Yunyun Liu ORCID logo *a  

* Corresponding authors

a College of Chemistry and Chemical Engineering, Jiangxi Normal University, Nanchang 330022, P. R. China
E-mail: chemliuyunyun@jxnu.edu.cn

Abstract

The one-pot reactions of acetyl chloride, o-halobenzoic acids and Wittig reagents providing 3-methyl isocoumarins have been furnished via tandem Wittig reaction, oxa-Michael addition and C–C cross coupling. Three new chemical bonds including one C–O, one C[double bond, length as m-dash]C and one C–C bond are generated via the catalysis of a simple copper salt for the heterocycle construction.

Graphical abstract: Copper-catalyzed one-pot reactions of acetyl chloride, o-halobenzoic acids and Wittig reagents toward 3-methyl isocoumarin synthesis

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Article information

DOI
https://doi.org/10.1039/C7RA06707K
Article type
Paper
Submitted
16 Jun 2017
Accepted
24 Jul 2017
First published
01 Aug 2017
This article is Open Access
Creative Commons BY-NC license

RSC Adv., 2017,7, 37839-37843

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Copper-catalyzed one-pot reactions of acetyl chloride, o-halobenzoic acids and Wittig reagents toward 3-methyl isocoumarin synthesis

X. Chen and Y. Liu, RSC Adv., 2017, 7, 37839 DOI: 10.1039/C7RA06707K

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