Issue 65, 2017, Issue in Progress

An indolizine–rhodamine based FRET fluorescence sensor for highly sensitive and selective detection of Hg2+ in living cells

Abstract

An indolizine–rhodamine-based ratiometric fluorescent probe was designed and successfully synthesized. The probe shows a large Stokes shift (204 nm), high sensitivity and high selectivity. The detection limit was calculated to be as low as 8.76 nM. The probe could quickly (5 min) detect Hg2+ over a wide pH range from 5 to 10. Furthermore, it could be used for imaging Hg2+ in living cells.

Graphical abstract: An indolizine–rhodamine based FRET fluorescence sensor for highly sensitive and selective detection of Hg2+ in living cells

Supplementary files

Article information

Article type
Paper
Submitted
19 Jul 2017
Accepted
16 Aug 2017
First published
22 Aug 2017
This article is Open Access
Creative Commons BY license

RSC Adv., 2017,7, 40829-40833

An indolizine–rhodamine based FRET fluorescence sensor for highly sensitive and selective detection of Hg2+ in living cells

R. Ji, A. Liu, S. Shen, X. Cao, F. Li and Y. Ge, RSC Adv., 2017, 7, 40829 DOI: 10.1039/C7RA07938A

This article is licensed under a Creative Commons Attribution 3.0 Unported Licence. You can use material from this article in other publications without requesting further permissions from the RSC, provided that the correct acknowledgement is given.

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