A heparin-mimicking biomolecule, β-cyclodextrin decorated with sulfonate groups (CD-S), was synthesized. CD-S itself exhibited bioactivity similar to that of heparin and can further serve as a carrier for all-trans retinoic acid by forming inclusion complexes that promote neural differentiation of embryonic stem cells more effectively than heparin.
Z. Lyu, X. Shi, J. Lei, Y. Yuan, L. Yuan, Q. Yu and H. Chen, J. Mater. Chem. B, 2017, 5, 1896 DOI: 10.1039/C6TB02572B
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