Issue 22, 2018

Preparation of a two-photon fluorescent probe with a large turn-on signal for imaging hypochlorous acid in living tissues

Abstract

We have rationally constructed a new two-photon fluorescent hypochlorous acid probe (TP-HA). The probe TP-HA displayed a fluorescence enhancement (∼16-fold) in response to HOCl with high sensitivity and selectivity. The new probe was membrane-permeable and suitable for visualization of the changes of HOCl in living cells and tissues.

Graphical abstract: Preparation of a two-photon fluorescent probe with a large turn-on signal for imaging hypochlorous acid in living tissues

Supplementary files

Article information

Article type
Communication
Submitted
20 Mar 2018
Accepted
08 May 2018
First published
10 May 2018

Anal. Methods, 2018,10, 2546-2550

Preparation of a two-photon fluorescent probe with a large turn-on signal for imaging hypochlorous acid in living tissues

K. Zhou, M. Ren, L. Wang, Z. Li and W. Lin, Anal. Methods, 2018, 10, 2546 DOI: 10.1039/C8AY00607E

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