Palladium-catalyzed oxidative allylation of bis[(pinacolato)boryl]methane: synthesis of homoallylic boronic esters

Abstract

A palladium-catalyzed oxidative allylation of bis[(pinacolato)boryl]methane to afford the corresponding homoallylic organoboronic esters with moderate to excellent yields is reported. This novel transformation provides an efficient strategy for the construction of homoallylic organoboronic esters in one step with a broad substrate scope. It is proposed that the palladium-catalyzed oxidative allylic C–H bond activation process may be involved in the catalytic cycle.