Issue 3, 2018
From the journal:

Chemical Communications

BEAMing LAMP: single-molecule capture and on-bead isothermal amplification for digital detection of hepatitis C virus in plasma†

Jiyun Chen,a   Xiaomin Xu,a   Zhimei Huang,a   Yuan Luo,a   Lijuan Tang*a  and  Jian-Hui Jiang ORCID logo *a  

* Corresponding authors

a State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, Hunan University, Changsha 410082, P. R. China
E-mail: jianhuijiang@hnu.edu.cn, tanglijuang@hnu.edu.cn

Abstract

A novel dNAD platform (BEAMing LAMP) by combining emulsion micro-reactors, single-molecule magnetic capture and on-bead loop-mediated isothermal amplification has been developed for DNA detection, which enables absolute and high-precision quantification of a target with a detection limit of 300 copies.

Graphical abstract: BEAMing LAMP: single-molecule capture and on-bead isothermal amplification for digital detection of hepatitis C virus in plasma

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Article information

DOI
https://doi.org/10.1039/C7CC08403J
Article type
Communication
Submitted
01 Nov 2017
Accepted
05 Dec 2017
First published
06 Dec 2017

Chem. Commun., 2018,54, 291-294

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BEAMing LAMP: single-molecule capture and on-bead isothermal amplification for digital detection of hepatitis C virus in plasma

J. Chen, X. Xu, Z. Huang, Y. Luo, L. Tang and J. Jiang, Chem. Commun., 2018, 54, 291 DOI: 10.1039/C7CC08403J

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