Issue 23, 2018
From the journal:

Chemical Communications

Super-resolution imaging of lysosomes with a nitroso-caged rhodamine†

Haihong He,‡a   Zhiwei Ye,‡b   Ying Zheng,b   Xiu Xu,a   Chunlei Guo,a   Yi Xiao,*b   Wei Yang,*b   Xuhong Qian*a  and  Youjun Yang ORCID logo *a  

* Corresponding authors

a State Key Laboratory of Bioreactor Engineering, Shanghai Key Laboratory of Chemical Biology, School of Pharmacy, East China University of Science and Technology, Shanghai, China
E-mail: xhqian@ecust.edu.cn, youjunyang@ecust.edu.cn

b State Key Laboratory of Fine Chemicals, Dalian University of Technology, Liaoning, China
E-mail: xiaoyi@dlut.edu.cn, yw917@dlut.edu.cn

Abstract

Caged-fluorophores are potentially suitable for photo-activated localization microscopy (PALM) for super-resolution imaging. N-Nitroso is a simple and robust photo-cage with biocompatible nitric oxide as the only byproduct upon photolysis. We herein reported a novel PALM probe (NOR535) for super-resolution imaging of lysosomes with high localization precision.

Graphical abstract: Super-resolution imaging of lysosomes with a nitroso-caged rhodamine

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Article information

DOI
https://doi.org/10.1039/C7CC08886H
Article type
Communication
Submitted
18 Nov 2017
Accepted
18 Jan 2018
First published
23 Jan 2018

Chem. Commun., 2018,54, 2842-2845

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Super-resolution imaging of lysosomes with a nitroso-caged rhodamine

H. He, Z. Ye, Y. Zheng, X. Xu, C. Guo, Y. Xiao, W. Yang, X. Qian and Y. Yang, Chem. Commun., 2018, 54, 2842 DOI: 10.1039/C7CC08886H

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