Issue 8, 2018
From the journal:

Chemical Communications

Circular DNA: a stable probe for highly efficient mRNA imaging and gene therapy in living cells†

Jingying Li,‡a   Jie Zhou,‡a   Tong Liu,a   Shan Chen,b   Juan Li*b  and  Huanghao Yang ORCID logo *b  

* Corresponding authors

a College of Biological Science and Engineering, Fuzhou University, Fuzhou 350116, P. R. China

b MOE Key Laboratory for Analytical Science of Food Safety and Biology, State Key Laboratory of Photocatalysis on Energy and Environment, College of Chemistry, Fuzhou University, Fuzhou 350116, P. R. China
E-mail: lijuan@fzu.edu.cn, hhyang@fzu.edu.cn

Abstract

Due to its high nuclease resistance and improved stability in biological fluids, circular DNA (cDNA) has been used to fabricate an intracellular mRNA sensing platform. cDNA has turned out to be a good option for highly efficient biosensing and therapeutics in living biological systems.

Graphical abstract: Circular DNA: a stable probe for highly efficient mRNA imaging and gene therapy in living cells

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Article information

DOI
https://doi.org/10.1039/C7CC08906F
Article type
Communication
Submitted
21 Nov 2017
Accepted
21 Dec 2017
First published
21 Dec 2017

Chem. Commun., 2018,54, 896-899

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Circular DNA: a stable probe for highly efficient mRNA imaging and gene therapy in living cells

J. Li, J. Zhou, T. Liu, S. Chen, J. Li and H. Yang, Chem. Commun., 2018, 54, 896 DOI: 10.1039/C7CC08906F

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