Issue 7, 2018
From the journal:

Chemical Communications

Ultrasensitive electrochemical immunoassay for melanoma cells using mesoporous polyaniline†

M. U. Anu Prathap,a   Carlos Iván Rodríguez,b   Omer Sadak,c   Jiehao Guan,a   Vijayasaradhi Setaluri*b  and  Sundaram Gunasekaran ORCID logo *ac  

* Corresponding authors

a Department of Biological Systems Engineering, University of Wisconsin-Madison, 460 H Mall, Madison, WI 53706, USA
E-mail: guna@wisc.edu

b Department of Dermatology, School of Medicine and Public Health, University of Wisconsin-Madison, 1300 University Avenue, B-25, Madison, WI 53706, USA
E-mail: vsetaluri@dermatology.wisc.edu

c Department of Materials Science and Engineering, University of Wisconsin-Madison, 1509 University Avenue, Madison, WI 53706, USA

Abstract

We report the development of an antibody (anti-MC1R antibody)-functionalized polyaniline nanofibers modified screen-printed electrode capable of efficient electrochemical detection of melanoma cells at levels (1 cell per mL) not readily achieved by other methods. This immunosensor is highly selective in its detection of melanoma cells over normal human cells.

Graphical abstract: Ultrasensitive electrochemical immunoassay for melanoma cells using mesoporous polyaniline

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Article information

DOI
https://doi.org/10.1039/C7CC09248B
Article type
Feature Article
Submitted
02 Dec 2017
Accepted
18 Dec 2017
First published
19 Dec 2017

Chem. Commun., 2018,54, 710-714

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Ultrasensitive electrochemical immunoassay for melanoma cells using mesoporous polyaniline

M. U. A. Prathap, C. I. Rodríguez, O. Sadak, J. Guan, V. Setaluri and S. Gunasekaran, Chem. Commun., 2018, 54, 710 DOI: 10.1039/C7CC09248B

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