Issue 21, 2018
From the journal:

Chemical Communications

Dean flow assisted cell ordering system for lipid profiling in single-cells using mass spectrometry†

Qiushi Huang, ORCID logo a   Sifeng Mao, ORCID logo a   Mashooq Khan, ORCID logo a   Lin Zhoua  and  Jin-Ming Lin ORCID logo *a  

* Corresponding authors

a Department of Chemistry, Beijing Key Laboratory of Micronalytical Methods and Instrumentation, MOE Key Laboratory of Bioorganic Phosphorus Chemistry & Chemical Biology, Tsinghua University, Beijing 100084, China
E-mail: jmlin@mail.tsinghua.edu.cn

Abstract

This study describes a novel Dean flow assisted cell ordering system which is connected to an electrospray ionization-mass spectrometer for the detection of lipids in a single-cell. This platform provides a facile method for direct analysis of label-free lipids in single-cells and significantly improves the efficiency of single-cell mass spectrometry.

Graphical abstract: Dean flow assisted cell ordering system for lipid profiling in single-cells using mass spectrometry

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Article information

DOI
https://doi.org/10.1039/C7CC09608A
Article type
Communication
Submitted
15 Dec 2017
Accepted
15 Jan 2018
First published
15 Jan 2018

Chem. Commun., 2018,54, 2595-2598

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Dean flow assisted cell ordering system for lipid profiling in single-cells using mass spectrometry

Q. Huang, S. Mao, M. Khan, L. Zhou and J. Lin, Chem. Commun., 2018, 54, 2595 DOI: 10.1039/C7CC09608A

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