A supramolecular self-assembly strategy for upconversion nanoparticle bioconjugation

Yulong Sun; Wenjing Zhang; Baoming Wang; Xiaoxue Xu; Joshua Chou; Olga Shimoni; Alison T. Ung; Dayong Jin

doi:10.1039/C8CC00708J

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A supramolecular self-assembly strategy for upconversion nanoparticle bioconjugation†

Yulong Sun,

^abc Wenjing Zhang,^acd Baoming Wang,

^ac Xiaoxue Xu,

^ac Joshua Chou,

^e Olga Shimoni,

*^abc Alison T. Ung

^c and Dayong Jin

*^abc

Author affiliations

* Corresponding authors

^a Institute of Biomedical Materials & Devices (IBMD), Faculty of Science, University of Technology Sydney, Ultimo, Sydney, NSW, Australia

^b ARC Research Hub of Integrated Device for End-user Analysis at Low-level (IDEAL), Faculty of Science, University of Technology Sydney, Ultimo, NSW, Australia

^c School of Mathematical and Physical Sciences, Faculty of Science, University of Technology Sydney, Ultimo, NSW, Australia

^d Institute of Advanced Materials for Nano-Bio Application, School of Ophthalmology and Optometry, Wenzhou Medical University, Wenzhou, Zhejiang, P. R. China

^e School of Life Science, Advanced Tissue Regeneration and Drug Delivery Group, Faculty of Science, University of Technology Sydney, Ultimo, NSW, Australia
E-mail: dayong.jin@uts.edu.au, olga.shimoni@uts.edu.au

Abstract

An efficient surface modification for upconversion nanoparticles (UCNPs) is reported via supramolecular host–guest self-assembly. Cucurbit[7]uril (CB) can provide a hydrophilic surface and cavities for most biomolecules. High biological efficiency, activity and versatility of the approach enable UCNPs to be significantly applied in bio-imaging, early disease detection, and bio-sensing.

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Article information

DOI: https://doi.org/10.1039/C8CC00708J
Article type: Communication
Submitted: 27 Jan 2018
Accepted: 19 Mar 2018
First published: 19 Mar 2018
This article is Open Access

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Chem. Commun., 2018,54, 3851-3854

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A supramolecular self-assembly strategy for upconversion nanoparticle bioconjugation

Y. Sun, W. Zhang, B. Wang, X. Xu, J. Chou, O. Shimoni, A. T. Ung and D. Jin, Chem. Commun., 2018, 54, 3851 DOI: 10.1039/C8CC00708J

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Chemical Communications

A supramolecular self-assembly strategy for upconversion nanoparticle bioconjugation†

Abstract

Supplementary files

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A supramolecular self-assembly strategy for upconversion nanoparticle bioconjugation

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