Issue 37, 2018

Electrophysiological measurements reveal that a succinyl linker enhances performance of the synthetic chloride channel SCMTR

Abstract

Four variants of a synthetic chloride anion channel composed of dialkyamines linked to a heptapeptide have been studied in different lipid and polymer membranes using electrophysiological techniques. For the first time, the values of conductance states, voltage gating properties, and qualitative state transition frequency were measured in different lipid systems.

Graphical abstract: Electrophysiological measurements reveal that a succinyl linker enhances performance of the synthetic chloride channel SCMTR

Article information

Article type
Communication
Submitted
26 Feb 2018
Accepted
10 Apr 2018
First published
13 Apr 2018

Chem. Commun., 2018,54, 4689-4691

Electrophysiological measurements reveal that a succinyl linker enhances performance of the synthetic chloride channel SCMTR

F. Minooei, M. D. Martin, J. R. Fried and J. P. Brian, Chem. Commun., 2018, 54, 4689 DOI: 10.1039/C8CC01565A

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