Issue 71, 2018

Water solubility is essential for fluorescent probes to image hypochlorous acid in live cells

Abstract

We synthesised four probes and compared their HClO-detecting ability in different solvents. The data showed that only hydrophilic probes could sensitively and accurately detect HClO in live cells. Meanwhile, the addition of organic solvents, as is commonly practised, weakens the oxidising capacity of HClO and thus generates inaccurate outcomes.

Graphical abstract: Water solubility is essential for fluorescent probes to image hypochlorous acid in live cells

Supplementary files

Article information

Article type
Communication
Submitted
11 Jun 2018
Accepted
19 Jul 2018
First published
19 Jul 2018

Chem. Commun., 2018,54, 9889-9892

Water solubility is essential for fluorescent probes to image hypochlorous acid in live cells

P. Xing, Z. Zhang, Y. Niu, Y. Qi, L. Dong and C. Wang, Chem. Commun., 2018, 54, 9889 DOI: 10.1039/C8CC04631J

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