Multifunctional supramolecular vesicles for combined photothermal/photodynamic/hypoxia-activated chemotherapy

Qi Wang; Lu Tian; Jingzeng Xu; Bing Xia; Jie Li; Feng Lu; Xiaomei Lu; Wenjun Wang; Wei Huang; Quli Fan

doi:10.1039/C8CC05560B

Multifunctional supramolecular vesicles for combined photothermal/photodynamic/hypoxia-activated chemotherapy†

Qi Wang,^a Lu Tian,^a Jingzeng Xu,^a Bing Xia,^a Jie Li,^a Feng Lu,

^a Xiaomei Lu,^b Wenjun Wang,^c Wei Huang^b and Quli Fan

*^a

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* Corresponding authors

^a Key Laboratory for Organic Electronics and Information Displays & Jiangsu Key Laboratory for Biosensors, Institute of Advanced Materials (IAM), Jiangsu National Synergetic Innovation Center for Advanced Materials (SICAM), Nanjing University of Posts & Telecommunications, Nanjing 210023, China
E-mail: iamqlfan@njupt.edu.cn

^b Key Laboratory of Flexible Electronics & Institute of Advanced Materials, Jiangsu National Synergetic Innovation Center for Advanced Materials, Nanjing Tech University (NanjingTech), Nanjing 211816, China

^c Key Lab of Optical Communication Science and Technology of Shandong Province & School of Physics Science and Information Engineering, Liaocheng University, Liaocheng 252059, China

Abstract

Multifunctional supramolecular vesicles were constructed by self-assembly of water-soluble pillar[5]arene and near infrared-absorbing guest G. They exhibited remarkable antitumor efficacy through simultaneous combination of photothermal, photodynamic and photodynamic-triggered hypoxia-activated chemotherapy.

Chemical Communications

Multifunctional supramolecular vesicles for combined photothermal/photodynamic/hypoxia-activated chemotherapy†

Abstract

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Multifunctional supramolecular vesicles for combined photothermal/photodynamic/hypoxia-activated chemotherapy

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