Issue 83, 2018

Expedient stereospecific Co-catalyzed tandem C–N and C–O bond formation of N-methylanilines with styrene oxides

Abstract

Cobalt(II)-catalyzed stereospecific coupling of N-methylanilines with styrene oxides is developed via tandem C–N and C–O bond formation using tert-butyl hydroperoxide (TBHP) as an oxidant. Optically active epoxide can be reacted with high optical purity.

Graphical abstract: Expedient stereospecific Co-catalyzed tandem C–N and C–O bond formation of N-methylanilines with styrene oxides

Supplementary files

Article information

Article type
Communication
Submitted
31 Jul 2018
Accepted
17 Sep 2018
First published
18 Sep 2018

Chem. Commun., 2018,54, 11813-11816

Expedient stereospecific Co-catalyzed tandem C–N and C–O bond formation of N-methylanilines with styrene oxides

V. Satheesh, S. Vivek Kumar and T. Punniyamurthy, Chem. Commun., 2018, 54, 11813 DOI: 10.1039/C8CC06223D

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