A ruthenium(ii) complex–cyanine energy transfer scaffold based luminescence probe for ratiometric detection and imaging of mitochondrial peroxynitrite†
Abstract
A novel ruthenium(II) complex–cyanine energy transfer scaffold has been established for the development of a ratiometric luminescence probe for ONOO− detection. The probe, Ru–Cy5, is localized in mitochondria of live cells, allowing ratiometric sensing and imaging of ONOO− therein.