Issue 44, 2018
From the journal:

Dalton Transactions

A novel mesoionic carbene based highly fluorescent Pd(ii) complex as an endoplasmic reticulum tracker in live cells†

Sanjay K. Verma, ORCID logo a   Pratibha Kumari, ORCID logo b   Shagufi Naz Ansari, ORCID logo a   Mohd Ovais Ansari,a   Dondinath Deoria  and  Shaikh M. Mobin ORCID logo *abc  

* Corresponding authors

a Discipline of Chemistry, India
E-mail: xray@iiti.ac.in

b Discipline of Biosciences and Biomedical Engineering, India

c Discipline of Metallurgy Engineering and Materials Science, Indian Institute of Technology Indore, Simrol, Khandwa Road, Indore 453552, India

Abstract

A recent study advocates that endoplasmic reticulum (ER) dysfunction may be linked to critical neurotrauma and advanced tauopathy. In this regard, targeting the ER warrants urgent attention towards the therapeutic treatment of neurotrauma-related neurodegeneration. Herein, we report the synthesis of a new N-heterocyclic mesoionic carbene based highly fluorescent square-planar Pd(II) complex 1, with a high quantum yield (0.737). Probe 1 is a non-toxic probe for selectively labeling the endoplasmic reticulum in live cells.

Graphical abstract: A novel mesoionic carbene based highly fluorescent Pd(ii) complex as an endoplasmic reticulum tracker in live cells

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Article information

DOI
https://doi.org/10.1039/C8DT02778A
Article type
Communication
Submitted
06 Jul 2018
Accepted
29 Aug 2018
First published
30 Aug 2018

Dalton Trans., 2018,47, 15646-15650

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A novel mesoionic carbene based highly fluorescent Pd(II) complex as an endoplasmic reticulum tracker in live cells

S. K. Verma, P. Kumari, S. N. Ansari, M. O. Ansari, D. Deori and S. M. Mobin, Dalton Trans., 2018, 47, 15646 DOI: 10.1039/C8DT02778A

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