Issue 4, 2018
From the journal:

Environmental Science: Nano

Human serum albumin stabilizes aqueous silver nanoparticle suspensions and inhibits particle uptake by cells†

D. C. Kennedy, ORCID logo *a   H. Qian, ORCID logo b   V. Giesa  and  L. Yang ORCID logo a  

* Corresponding authors

a Measurement Science and Standards, National Research Council Canada, 1200 Montreal Road, Ottawa K1A 0R6, Canada
E-mail: david.kennedy@nrc-cnrc.gc.ca

b National Institute for Nanotechnology, 11421 Saskatchewan Dr NW, Edmonton, AB T6G 2M9, Canada

Abstract

Incubation of 20 nm silver nanoparticles with human serum albumin (HSA) stabilizes the nanoparticles against aggregation and dissolution and produces particles that can be lyophilized for longterm storage and redispersed in water consistently. Biological studies of this stabilized material showed reduced toxicity and cellular uptake compared to other 20 nm particles.

Graphical abstract: Human serum albumin stabilizes aqueous silver nanoparticle suspensions and inhibits particle uptake by cells

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Article information

DOI
https://doi.org/10.1039/C8EN00087E
Article type
Communication
Submitted
18 Jan 2018
Accepted
20 Feb 2018
First published
16 Mar 2018

Environ. Sci.: Nano, 2018,5, 863-867

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Human serum albumin stabilizes aqueous silver nanoparticle suspensions and inhibits particle uptake by cells

D. C. Kennedy, H. Qian, V. Gies and L. Yang, Environ. Sci.: Nano, 2018, 5, 863 DOI: 10.1039/C8EN00087E

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