A KI-mediated radical anti-Markovnikov addition of simple ketones/esters to unactivated alkenes

Abstract

A KI-mediated radical anti-Markovnikov addition of simple ketones and esters to unactivated alkenes was developed. Through this strategy, a wide range of complex carbonyl compounds can be conveniently synthesized in high selectivities. In addition, this method features high atom-economy and is transition-metal free, operationally simple and environmentally benign.