Issue 45, 2018
From the journal:

Nanoscale

Superwettable nanodendritic gold substrates for direct miRNA SERS detection†

Yongchao Song,a   Tailin Xu, ORCID logo *a   Li-Ping Xu*a  and  Xueji Zhang*a  

* Corresponding authors

a Research Center for Bioengineering and Sensing Technology, School of Chemistry and Biological Engineering, University of Science and Technology Beijing, Beijing 100083, P. R. China
E-mail: xutailin@ustb.edu.cn, xuliping@ustb.edu.cn, zhangxueji@ustb.edu.cn

Abstract

By combining a superwettable interface with a nanodendritic gold structure, we have fabricated a superwettable nanodendritic gold substrate for direct SERS detection of multiple concentrations of miRNAs. The nanodendritic gold substrate provides numerous hotspots for Raman signal enhancement, and the superwettable interface ensures the immobilization of droplets in superhydrophilic microwells, which hold great potentials for applications in disease diagnostics.

Graphical abstract: Superwettable nanodendritic gold substrates for direct miRNA SERS detection

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Article information

DOI
https://doi.org/10.1039/C8NR07348A
Article type
Communication
Submitted
10 Sep 2018
Accepted
24 Oct 2018
First published
25 Oct 2018

Nanoscale, 2018,10, 20990-20994

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Superwettable nanodendritic gold substrates for direct miRNA SERS detection

Y. Song, T. Xu, L. Xu and X. Zhang, Nanoscale, 2018, 10, 20990 DOI: 10.1039/C8NR07348A

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