Issue 2, 2018

Total synthesis of selaginpulvilins A and C

Abstract

An efficient formal total synthesis of two compounds from the selaginpulvilin family of natural products, selaginpulvilin A and C, has been successfully achieved. The tetradehydro Diels–Alder (TDDA) reaction between an enyne and alkyne has been utilized for the creation of the necessary fluorene skeleton. Attempts at the conversion of selaginpulvilin A to selaginpulvilin B, F and H were unsuccessful.

Graphical abstract: Total synthesis of selaginpulvilins A and C

Supplementary files

Article information

Article type
Paper
Submitted
24 Oct 2017
Accepted
01 Dec 2017
First published
01 Dec 2017

Org. Biomol. Chem., 2018,16, 262-265

Total synthesis of selaginpulvilins A and C

B. S. Chinta and B. Baire, Org. Biomol. Chem., 2018, 16, 262 DOI: 10.1039/C7OB02609A

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