Issue 2, 2018

Palladium-catalyzed synthesis of fluoreones from bis(2-bromophenyl)methanols

Abstract

A palladium-catalyzed synthesis method of fluorenones has been developed. A variety of bis(2-bromophenyl)methanols could undergo the reaction smoothly in the presence of Pd(OAc)2, affording a series of fluorenones in moderate to good yields (two steps). Mechanistic studies reveal that the reaction might be triggered by oxidation of alcohol followed by intramolecular reductive coupling.

Graphical abstract: Palladium-catalyzed synthesis of fluoreones from bis(2-bromophenyl)methanols

Supplementary files

Article information

Article type
Communication
Submitted
23 Nov 2017
Accepted
12 Dec 2017
First published
12 Dec 2017

Org. Biomol. Chem., 2018,16, 208-212

Palladium-catalyzed synthesis of fluoreones from bis(2-bromophenyl)methanols

Q. Gao and S. Xu, Org. Biomol. Chem., 2018, 16, 208 DOI: 10.1039/C7OB02895D

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