Issue 6, 2018

Specific labeling of mitochondria of Chlamydomonas with cationic helicene fluorophores

Abstract

Twelve cationic helicenes and one triangulene were tested for the specific labeling of mitochondria from algal cells. Octyl ester derivative 5 readily penetrates algal cells and gives rise to clear fluorescence patterns when it is used at concentrations in the μM range. Under these conditions, cell structures are well preserved and cell survival is not compromised. Cationic helicene compounds such as 5 provide new useful tools for examining the mitochondrial network and its dynamics including fission and fusion events.

Graphical abstract: Specific labeling of mitochondria of Chlamydomonas with cationic helicene fluorophores

Supplementary files

Article information

Article type
Paper
Submitted
24 Nov 2017
Accepted
09 Jan 2018
First published
09 Jan 2018

Org. Biomol. Chem., 2018,16, 919-923

Specific labeling of mitochondria of Chlamydomonas with cationic helicene fluorophores

C. Bauer, R. Duwald, G. M. Labrador, S. Pascal, P. Moneva Lorente, J. Bosson, J. Lacour and J. Rochaix, Org. Biomol. Chem., 2018, 16, 919 DOI: 10.1039/C7OB02906C

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