Issue 5, 2018

Rhodium-catalyzed C7-alkylation of indolines with maleimides

Abstract

A rhodium(III)-catalyzed direct cross-coupling reaction of indolines with maleimides via C–H bond activation was developed. This protocol displays good functional group tolerance, which offers a novel approach to access C7 modified indoline derivatives including maleimide analogues.

Graphical abstract: Rhodium-catalyzed C7-alkylation of indolines with maleimides

Supplementary files

Article information

Article type
Communication
Submitted
08 Dec 2017
Accepted
03 Jan 2018
First published
03 Jan 2018

Org. Biomol. Chem., 2018,16, 693-697

Rhodium-catalyzed C7-alkylation of indolines with maleimides

C. Pan, Y. Wang, C. Wu and J. Yu, Org. Biomol. Chem., 2018, 16, 693 DOI: 10.1039/C7OB03039H

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