Iridium-catalyzed C–H phosphoramidation of N-aryl-7-azaindoles with phosphoryl azides

Abstract

An iridium-catalyzed C–H phosphoramidation of N-aryl-7-azaindoles with phosphoryl azides was developed, affording a series of 7-azaindole phenylphosphoramidates in moderate to good yields. This protocol displays good functional group tolerance, which offers a novel and direct approach to access 7-azaindole phenylphosphoramidates.