Rh(iii)-Catalyzed α-fluoroalkenylation of N-nitrosoanilines with 2,2-difluorovinyl tosylates via C–H bond activation

Abstract

Rh(III)-Catalyzed α-fluoroalkenylation of N-nitrosoanilines with 2,2-difluorovinyl tosylates has been realized. This reaction proceeded via chelation-assisted C–H activation, olefin insertion and β-F elimination, leading to the synthesis of monofluoroalkenes with high Z-selectivity with respect to the olefin. This catalytic system is highly efficient over a broad range of substrates under mild and redox-neutral conditions.