Issue 16, 2018, Issue in Progress
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RSC Advances

Exploring the trans-membrane dynamic mechanisms of single polyamidoamine nano-drugs via a “force tracing” technique†

Siyuan Zhou,a   Boyu Yang,a   Yang Chen,a   Qingrong Zhang,a   Mingjun Cai,b   Haijiao Xu,b   Guocheng Yang,a   Hongda Wang ORCID logo *bc  and  Yuping Shan*a  

* Corresponding authors

a School of Chemistry and Life Science, Advanced Institute of Materials Science, Changchun University of Technology, Changchun 130012, China
E-mail: shanyp@ciac.ac.cn

b Changchun Institute of Applied Chemistry, Chinese Academy of Science, Renmin St 5625, Changchun, China
E-mail: hdwang@ciac.ac.cn

c University of Chinese Academy of Sciences, Beijing, China

Abstract

Considerable technological success has been achieved in the drug delivery of nano-drugs for chemotherapy, but the main obstacles in understanding the drug delivery dynamic mechanisms for nano-drug applications stem from technical limitations. In this paper, we explored the trans-membrane dynamic processes of polyamidoamine nano-drugs via a “force tracing” technique.

Graphical abstract: Exploring the trans-membrane dynamic mechanisms of single polyamidoamine nano-drugs via a “force tracing” technique

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Article information

DOI
https://doi.org/10.1039/C8RA00134K
Article type
Paper
Submitted
26 Jan 2018
Accepted
07 Feb 2018
First published
27 Feb 2018
This article is Open Access
Creative Commons BY-NC license

RSC Adv., 2018,8, 8626-8630

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Exploring the trans-membrane dynamic mechanisms of single polyamidoamine nano-drugs via a “force tracing” technique

S. Zhou, B. Yang, Y. Chen, Q. Zhang, M. Cai, H. Xu, G. Yang, H. Wang and Y. Shan, RSC Adv., 2018, 8, 8626 DOI: 10.1039/C8RA00134K

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