Polymer encapsulation of anticancer silver–N-heterocyclic carbene complexes†
P. D.
Thornton 
*a
and
C. E.
Willans
*a
*a
and
C. E.
Willans
*a
Abstract
Amphiphilic block copolymers have been developed for the encapsulation of organometallic drugs. silver–N-heterocyclic carbene complexes have shown significant promise as anticancer and antibacterial compounds, and have been studied as the payload in these carriers. Simple modification of the N-heterocyclic carbene ligand structure enables solubility properties and interaction with the polymer to be tuned.
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