Iodine-promoted three-component synthesis of substituted β-amino sulfides has been developed starting from a propargyl ester, aliphatic secondary amine, and disulfide. This protocol provides a step-economic and highly regioselective entry to trisubstituted olefins with good substrate scope and functional group tolerance.
F. Xiao, D. Wang, S. Yuan, H. Huang and G. Deng, RSC Adv., 2018, 8, 23319 DOI: 10.1039/C8RA04374D
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