Issue 55, 2018, Issue in Progress
From the journal:

RSC Advances

Polyellisin, a novel polyketide from cultures of the basidiomycete Polyporus ellisii†

Shuang Wang,ab   Zheng-Hui Li,a   Hong-Lian Ai,a   Juan He,a   Tao Feng ORCID logo *a  and  Ji-Kai Liu*a  

* Corresponding authors

a School of Pharmaceutical Sciences, South-Central University for Nationalities, Wuhan 430074, China
E-mail: tfeng@mail.scuec.edu.cn, jkliu@mail.kib.ac.cn

b College of Pharmacy and Chemistry, Dali University, Dali 671000, China

Abstract

Polyellisin (1), an unprecedented polyketide possessing a tricyclic system sharing a spiroketal carbon, was isolated from cultures of the basidiomycete Polyporus ellisii. The structure with absolute configuration was elucidated by means of spectroscopic methods and the single crystal X-ray diffraction. Polyellisin showed NO production inhibition with an IC50 value of 17.2 μM.

Graphical abstract: Polyellisin, a novel polyketide from cultures of the basidiomycete Polyporus ellisii

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Article information

DOI
https://doi.org/10.1039/C8RA06544F
Article type
Paper
Submitted
03 Aug 2018
Accepted
04 Sep 2018
First published
10 Sep 2018
This article is Open Access
Creative Commons BY-NC license

RSC Adv., 2018,8, 31538-31541

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Polyellisin, a novel polyketide from cultures of the basidiomycete Polyporus ellisii

S. Wang, Z. Li, H. Ai, J. He, T. Feng and J. Liu, RSC Adv., 2018, 8, 31538 DOI: 10.1039/C8RA06544F

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