Issue 63, 2018, Issue in Progress
From the journal:

RSC Advances

Electrochemiluminescence of gold nanoparticles and gold nanoparticle-labelled antibodies as co-reactants

Changzhi Zhao, ORCID logo *ab   Lulu Niu,a   Xiaoyu Wanga  and  Wei Sun ORCID logo b  

* Corresponding authors

a Key Laboratory of Sensor Analysis of Tumor Marker, The Ministry of Education, College of Chemistry & Molecular Engineering, Qingdao University of Science & Technology, Qingdao 266042, China
E-mail: czzhao@qust.edu.cn

b Key Laboratory of Functional Materials and Photoelectronchemistry of Haikou, College of Chemistry and Chemical Engineering, Hainan Normal University, Haikou 571158, China
E-mail: swyy26@hotmail.com

Abstract

Gold nanoparticles (AuNPs) and AuNP-labelled antibodies can participate in the electrochemiluminescence (ECL) reaction of tris(2,2′-bipyridyl) ruthenium(II) (Ru(bpy)32+) as a co-reactant. The electrochemical and spectral characteristics of this new ECL system were confirmed by experiments, and its reaction mechanism was speculated to be different from that of typical ECL. The experimental results showed that the new ECL system exhibited higher ECL efficiency, and AuNP-labelled substances can be sensitively measured with the help of AuNPs. Based on the dual role of AuNPs as a co-reactant and marker, the AuNP–Ru(bpy)32+ ECL system will be a useful tool in biochemical analysis.

Graphical abstract: Electrochemiluminescence of gold nanoparticles and gold nanoparticle-labelled antibodies as co-reactants

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Article information

DOI
https://doi.org/10.1039/C8RA07429A
Article type
Paper
Submitted
06 Sep 2018
Accepted
07 Oct 2018
First published
24 Oct 2018
This article is Open Access
Creative Commons BY-NC license

RSC Adv., 2018,8, 36219-36222

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Electrochemiluminescence of gold nanoparticles and gold nanoparticle-labelled antibodies as co-reactants

C. Zhao, L. Niu, X. Wang and W. Sun, RSC Adv., 2018, 8, 36219 DOI: 10.1039/C8RA07429A

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