Issue 34, 2018

Rational design of Fe3O4@C nanoparticles for simultaneous bimodal imaging and chemo-photothermal therapy in vitro and in vivo

Abstract

We report a facile strategy to fabricate well-dispersed Fe3O4@C eccentric core–shell nanoparticles (NPs). The resulting Fe3O4@C eccentric core–shell NPs possess a high payload of doxorubicin (DOX) for use as synergetic pH/near-infrared (NIR)-sensitive drug delivery vehicles, and were applied for dual-modal magnetic resonance imaging (MRI)/photoacoustic imaging (PAI) and synergistic photothermal cancer therapy in vitro and in vivo.

Graphical abstract: Rational design of Fe3O4@C nanoparticles for simultaneous bimodal imaging and chemo-photothermal therapy in vitro and in vivo

Associated articles

Supplementary files

Article information

Article type
Paper
Submitted
04 May 2018
Accepted
06 Aug 2018
First published
11 Aug 2018

J. Mater. Chem. B, 2018,6, 5443-5450

Rational design of Fe3O4@C nanoparticles for simultaneous bimodal imaging and chemo-photothermal therapy in vitro and in vivo

Q. Han, X. Wang, Z. Sun, X. Xu, L. Jin, L. Qiao and Q. Yuan, J. Mater. Chem. B, 2018, 6, 5443 DOI: 10.1039/C8TB01184B

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