Issue 47, 2018

CO2-Acidolysis of iminoboronate ester based polymersomes

Abstract

Due to the very weak acidity of CO2 in water, it is highly interesting to fabricate CO2-responsive polymersomes which have both CO2-protonatable tertiary amines and CO2-hydrolyzable iminoboronate-linked drugs. Upon CO2 addition, amine protonation and iminoboronate hydrolysis simultaneously occur, leading to prominent vesicle disassembly and a tunable release feature.

Graphical abstract: CO2-Acidolysis of iminoboronate ester based polymersomes

Supplementary files

Article information

Article type
Communication
Submitted
23 Sep 2018
Accepted
22 Oct 2018
First published
22 Oct 2018

J. Mater. Chem. B, 2018,6, 7800-7804

CO2-Acidolysis of iminoboronate ester based polymersomes

R. Cheng, G. Li, L. Fan, Z. Liu, Z. Liu and J. Jiang, J. Mater. Chem. B, 2018, 6, 7800 DOI: 10.1039/C8TB02496K

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