A novel fluorescent turn-on probe for imaging biothiols based on SNAr substitution-skeletal rearrangement strategy†
Abstract
A novel fluorescent turn-on probe 2 not only exhibited dramatic fluorescence enhancement by quinoline-to-quinolinone transformation, but also showed high sensitivity in the order Cys > GSH > Hcy. Importantly, 2 was successfully applied for imaging of biothiols in living cells.