Issue 2, 2019
From the journal:

Analytical Methods

Fast and sensitive fluorescent probe for ratiometric detection of hydrogen sulfide in mitochondria†

Na Jiang, ORCID logo *a   Bin Wang,a   Tao Liu,b   Qingyu Liu,a   Qin Wei,a   Yujing Xinga  and  Gengxiu Zheng*a  

* Corresponding authors

a School of Chemistry and Chemical Engineering, University of Jinan, 336 Nanxinzhuang West Road, Jinan, China
E-mail: chm_jiangn@ujn.edu.cn, chm_zhenggx@ujn.edu.cn

b Department of Chemical Engineering, Chengde Petroleum College, Chengde, China

Abstract

A probe Mito-BT was constructed and synthesized by combining triphenylamine and hemicyanine, and can be used for specific ratiometric sensing of H2S. It has a rapid response time of 10 s and preferentially targets to mitochondria. Then the visualization of the change of the mitochondrial H2S concentration upon NaHS incubation by using Mito-BT staining is promising for the practical exploration of H2S-related processes in mitochondria.

Graphical abstract: Fast and sensitive fluorescent probe for ratiometric detection of hydrogen sulfide in mitochondria

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Supplementary files

Article information

DOI
https://doi.org/10.1039/C8AY02586J
Article type
Paper
Submitted
27 Nov 2018
Accepted
06 Dec 2018
First published
07 Dec 2018

Anal. Methods, 2019,11, 232-235

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Fast and sensitive fluorescent probe for ratiometric detection of hydrogen sulfide in mitochondria

N. Jiang, B. Wang, T. Liu, Q. Liu, Q. Wei, Y. Xing and G. Zheng, Anal. Methods, 2019, 11, 232 DOI: 10.1039/C8AY02586J

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