Diagnosis of penicillin allergy: a MOFs-based composite hydrogel for detecting β-lactamase in serum

Abstract

An as-synthesized MOFs-based hydrogel exhibits high sensitivity for β-lactamase through an “ON–OFF–OFF–ON” luminescence trigger. It allows achieving an unprecedented strategy for the judgement of penicillin allergy via luminescence detection of β-lactamase in serum.