The chiral interfaces fabricated by d/l-alanine-pillar[5]arenes for selectively adsorbing ctDNA

Abstract

In this paper, the D/L-AP5-interfaces are firstly fabricated by attaching D-alanine-pillar[5]arene and L-alanine-pillar[5]arene (D/L-AP5) onto the gold surface, and they exhibit a significantly different chiral influence on the morphology and the adsorption quantity of the adsorbed ctDNA molecules. The research provides an ideal chiral platform for investigating chiral phenomena in biological systems.