Issue 15, 2019

Homogenous deposition of matrix–analyte cocrystals on gold-nanobowl arrays for improving MALDI-MS signal reproducibility

Abstract

The non-uniform deposition of matrix–analyte cocrystals and poor ionization are major obstacles in quantitative analysis through MALDI-MS. An Au-nanobowl array was prepared and applied to overcome these limitations, which enabled the quantitative detection of oligonucleotides and polypeptides.

Graphical abstract: Homogenous deposition of matrix–analyte cocrystals on gold-nanobowl arrays for improving MALDI-MS signal reproducibility

Supplementary files

Article information

Article type
Communication
Submitted
18 Dec 2018
Accepted
15 Jan 2019
First published
22 Jan 2019

Chem. Commun., 2019,55, 2166-2169

Homogenous deposition of matrix–analyte cocrystals on gold-nanobowl arrays for improving MALDI-MS signal reproducibility

W. Li, M. Khan, H. Li, L. Lin, S. Mao and J. Lin, Chem. Commun., 2019, 55, 2166 DOI: 10.1039/C8CC09945F

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements