Issue 49, 2019

Nanofocused synchrotron X-ray absorption studies of the intracellular redox state of an organometallic complex in cancer cells

Abstract

Synchrotron nanoprobe X-ray absorption (XAS) studies of a potent organo-osmium arene anticancer complex in ovarian cancer cells at subcellular resolution allow detection and quantification of both OsII and OsIII species, which are distributed heterogeneously in different areas of the cells.

Graphical abstract: Nanofocused synchrotron X-ray absorption studies of the intracellular redox state of an organometallic complex in cancer cells

Supplementary files

Article information

Article type
Communication
Submitted
27 Feb 2019
Accepted
01 May 2019
First published
31 May 2019
This article is Open Access
Creative Commons BY license

Chem. Commun., 2019,55, 7065-7068

Nanofocused synchrotron X-ray absorption studies of the intracellular redox state of an organometallic complex in cancer cells

C. Sanchez-Cano, D. Gianolio, I. Romero-Canelon, R. Tucoulou and P. J. Sadler, Chem. Commun., 2019, 55, 7065 DOI: 10.1039/C9CC01675A

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