Issue 40, 2019
From the journal:

Chemical Communications

Immobilization of amidase into a magnetic hierarchically porous metal–organic framework for efficient biocatalysis†

Chaoping Lin,ab   Kongliang Xu,ab   Renchao Zheng ORCID logo *ab  and  Yuguo Zheng ORCID logo ab  

* Corresponding authors

a Key Laboratory of Bioorganic Synthesis of Zhejiang Province, College of Biotechnology and Bioengineering, Zhejiang University of Technology, Hangzhou 310014, China
E-mail: zhengrc@zjut.edu.cn
Fax: +86-571-88320884
Tel: +86-571-88320391

b Engineering Research Center of Bioconversion and Biopurification of Ministry of Education, Zhejiang University of Technology, Hangzhou 310014, China

Abstract

A novel magnetic hierarchically porous metal–organic framework (MOF) has been successfully fabricated via a modulator-induced defect-formation strategy. Amidase for the first time has been immobilized into this magnetic carrier and the resultant bio-composite exhibits superior enzymatic catalysis performance compared to the free enzyme and its counterparts without hierarchical porosity.

Graphical abstract: Immobilization of amidase into a magnetic hierarchically porous metal–organic framework for efficient biocatalysis

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Article information

DOI
https://doi.org/10.1039/C9CC02038A
Article type
Communication
Submitted
13 Mar 2019
Accepted
16 Apr 2019
First published
16 Apr 2019

Chem. Commun., 2019,55, 5697-5700

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Immobilization of amidase into a magnetic hierarchically porous metal–organic framework for efficient biocatalysis

C. Lin, K. Xu, R. Zheng and Y. Zheng, Chem. Commun., 2019, 55, 5697 DOI: 10.1039/C9CC02038A

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