Synthesis of an efficient far-red/near-infrared luminogen with AIE characteristics for in vivo bioimaging applications

Wei Qin; Nuernisha Alifu; Yuanjing Cai; Jacky W. Y. Lam; Xuewen He; Huifang Su; Pengfei Zhang; Jun Qian; Ben Zhong Tang

doi:10.1039/C9CC02238D

Synthesis of an efficient far-red/near-infrared luminogen with AIE characteristics for in vivo bioimaging applications†

Wei Qin,‡^a Nuernisha Alifu,‡^b Yuanjing Cai,

^c Jacky W. Y. Lam,^a Xuewen He,^a Huifang Su,^a Pengfei Zhang,

^a Jun Qian

*^b and Ben Zhong Tang

*^ade

Author affiliations

* Corresponding authors

^a Department of Chemistry, Hong Kong Branch of Chinese National Engineering Research Centre for Tissue Restoration and Reconstruction, Institute for Advanced Study, Institute of Molecular Functional Materials, Division of Biomedical Engineering, State Key Laboratory of Molecular Neuroscience, Division of Life Science, Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong
E-mail: tangbenz@ust.hk

^b State Key Laboratory of Modern Optical Instrumentations, Center for Optical and Electromagnetic Research, JORCEP (Sino-Swedish Joint Research Center of Photonics), Zhejiang University, Hangzhou 310058, China
E-mail: qianjun@zju.edu.cn

^c Beijing Advanced Innovation Center for Soft Matter Science and Engineering, Beijing University of Chemical Technology, Beijing 100029, China

^d Centre for Aggregation-Induced Emission, SCUT-HKUST Joint Research Laboratory, State Key Laboratory of Luminescent Materials and Devices, South China University of Technology, Guangzhou 510640, China

^e HKUST Shenzhen Research Institute, No. 9 Yuexing 1st RD, South Area Hi-tech Park, Nanshan, Shenzhen 518057, China

Abstract

A selenium-containing FR/NIR AIE luminogen with efficient solid-state emission is reported. Its AIE dots exhibit high brightness, large Stokes shift, good biocompatibility and satisfactory photostability, making them the first selenium-containing FR/NIR nanoprobes with AIE characteristics for in vivo bioimaging applications with high contrast and a high penetration depth.

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Article information

DOI: https://doi.org/10.1039/C9CC02238D
Article type: Communication
Submitted: 21 Mar 2019
Accepted: 10 Apr 2019
First published: 10 Apr 2019

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Chem. Commun., 2019,55, 5615-5618

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Synthesis of an efficient far-red/near-infrared luminogen with AIE characteristics for in vivo bioimaging applications

W. Qin, N. Alifu, Y. Cai, J. W. Y. Lam, X. He, H. Su, P. Zhang, J. Qian and B. Z. Tang, Chem. Commun., 2019, 55, 5615 DOI: 10.1039/C9CC02238D

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Chemical Communications

Synthesis of an efficient far-red/near-infrared luminogen with AIE characteristics for in vivo bioimaging applications†

Abstract

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Synthesis of an efficient far-red/near-infrared luminogen with AIE characteristics for in vivo bioimaging applications

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