Issue 49, 2019
From the journal:

Chemical Communications

Complementary interaction with peptide amphiphiles guides size-controlled assembly of small molecules for intracellular delivery†

Rie Wakabayashi, ORCID logo ‡*a   Hiroki Obayashi,‡a   Ryuichiro Hashimoto,a   Noriho Kamiya ORCID logo ab  and  Masahiro Goto ORCID logo *ab  

* Corresponding authors

a Department of Applied Chemistry, Graduate School of Engineering, Kyushu University, 744 Motooka, Nishi-ku, Fukuoka 819-0395, Japan
E-mail: rie_wakaba@mail.cstm.kyushu-u.ac.jp, m-goto@mail.cstm.kyushu-u.ac.jp

b Center for Future Chemistry, Kyushu University, 744 Motooka, Nishi-ku, Fukuoka 819-0395, Japan

Abstract

We introduced complementary interactions between peptide amphiphiles and a small fluorescence dye to develop a programmable multi-component supramolecular assembly, and intracellular delivery of the dye was controlled by the dimensions of the co-assembly, which was manipulated by the peptide design.

Graphical abstract: Complementary interaction with peptide amphiphiles guides size-controlled assembly of small molecules for intracellular delivery

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Article information

DOI
https://doi.org/10.1039/C9CC02473E
Article type
Communication
Submitted
30 Mar 2019
Accepted
13 May 2019
First published
13 May 2019

Chem. Commun., 2019,55, 6997-7000

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Complementary interaction with peptide amphiphiles guides size-controlled assembly of small molecules for intracellular delivery

R. Wakabayashi, H. Obayashi, R. Hashimoto, N. Kamiya and M. Goto, Chem. Commun., 2019, 55, 6997 DOI: 10.1039/C9CC02473E

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