Issue 49, 2019

Pd-catalysed selective C(sp3)–H arylation and acetoxylation of alcohols

Abstract

A palladium catalyzed selective C(sp3)–H arylation and acetoxylation of alcohols using a practical bidentate auxiliary were developed. Masked alcohols were selectively arylated at the β-position with diverse aryl iodides for the first time. Moreover, an efficient and site-selective acetoxylation of various primary methyl, methylene, and benzylic C(sp3)–H bonds was performed by using cheap K2S2O8 as the external oxidant.

Graphical abstract: Pd-catalysed selective C(sp3)–H arylation and acetoxylation of alcohols

Supplementary files

Article information

Article type
Communication
Submitted
15 Apr 2019
Accepted
21 May 2019
First published
22 May 2019

Chem. Commun., 2019,55, 7049-7052

Pd-catalysed selective C(sp3)–H arylation and acetoxylation of alcohols

B. Wang, Y. Mao, H. Hao, Q. Wu, K. Zhou, S. Lou and D. Xu, Chem. Commun., 2019, 55, 7049 DOI: 10.1039/C9CC02911G

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements