DNAzyme activated protein-scaffolded CRISPR–Cas9 nanoassembly for genome editing†
Abstract
A novel self-assembled protein-scaffolded CRISPR–Cas9 nanosystem for facile and efficient gene editing in a DNAzyme-controlled manner has been developed.
* Corresponding authors
a
Institute of Chemical Biology and Nanomedicine, State Key Laboratory of Chemo/Bio-Sensing and Chemometrics, College of Chemistry and Chemical Engineering, Hunan University, Changsha 410082, P. R. China
E-mail:
jinwenliu@hnu.edu.cn, jianhuijiang@hnu.edu.cn
Fax: +86-731-88822872
Tel: +86-731-88822577
A novel self-assembled protein-scaffolded CRISPR–Cas9 nanosystem for facile and efficient gene editing in a DNAzyme-controlled manner has been developed.
X. Zhu, M. Lv, J. Liu, R. Yu and J. Jiang, Chem. Commun., 2019, 55, 6511 DOI: 10.1039/C9CC03172C
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